Oralne manifestacije u pedijatrijskih bolesnika zaraženih virusom humane imunodefi cijencije na antiretrovirusnoj terapiji i bez nje: presječno istraživanje

摘要

The aim of the study was to assess and compare oral manifestations of human immunodefi ciency virus (HIV) infected pediatricpatients undergoing antiretroviral therapy (ART) and those not undergoing ART. A cross sectional study included HIV positive children(receiving and not receiving ART) aged 5-15 years, registered at the District Hospital ART Centre, Udaipur, and HIV negativeschoolchildren. HIV related oral lesions were diagnosed according to the World Health Organization criteria. Sociodemographic andother related information were also recorded. CD4+ cell count was determined in all study subjects. The χ2-test, stepwise multiplelinear regression and logistic regression were used on statistical analysis. In all tests, confi dence interval and p-value were set at 95%and ≤0.05, respectively. A greater proportion of HIV patients receiving treatment had CD4+ cell count of more than 750 cells/mm3.The majority of HIV patients receiving ART for more than three years and only 20% of those not receiving ART were free from any orallesions. The results of the present study demonstrated ART to be eff ective in reducing the prevalence of HIV related oral lesions, asalready described in the literature; however, unlike previous studies, the present paper reports more valid fi ndings for having includedmost of the confounding variables